Jim Levenstein (Jason Biggs) and his wife Michelle are dealing with a marital slump nine years after their wedding, while Kevin Myers (Thomas Ian Nicholas) is embracing domesticity as a househusband and architect. Their high school friend Chris "Oz" Ostreicher (Chris Klein) returns from a traveling career as a celebrity sportscaster, and they're all reunited in East Great Falls, Michigan, for their 13-year-old high school reunion. The group's dynamics are tested when they encounter Kara (Ali Cobrin), a former babysitter who sparks old feelings in Jim, leading to some awkward encounters and eventually, healing and reconciliation among the friends.