In "Vacancy 2: The First Cut," Jessica (Agnes Bruckner) checks into the Meadow View Inn for a night's rest, unaware of its sick-minded employees and their nefarious intentions. A man, Smith, brutally murders a woman he brought with him in the motel room, prompting the staff to attack and hire him to torture and murder guests. As Jessica and her friends try to escape, they are pursued by Smith and his accomplices, leading to a desperate fight for survival.