In "Cartagena", a poignant drama unfolds in a small Colombian town, where a beautiful and free-spirited woman becomes bedridden after a terrible accident. Against her better judgment, she hires a desperate, unqualified middle-aged ex-boxer to cook and care for her, but he slowly wins her trust through his quiet strength and gentle kindness. As they grow closer, the boundaries between caregiver and cared-for begin to blur, and the woman is forced to confront the joys of life beyond her window, thanks in part to the unlikely influence of literature - specifically the works of Charles Bukowski.