A ragtag group of Australia's deadliest creatures plot an escape from their zoo to the Outback, a place where they'll fit in without being judged. Maddie, Isla Fisher, and her friends, including Pretty Boy, Tim Minchin, Eric Bana, Guy Pearce, Miranda Tapsell, Angus Imrie, Keith Urban, and Jacki Weaver, work together to achieve their goal. Along the way, they meet various creatures who aid them in their journey, including a friendly great white shark named Jacinta.