American Dad!
The series focuses on an eccentric motley crew that is the Smith family and their three housemates: Father, husband, and breadwinner Stan Smith; his better half housewife, Francine Smith; their college-aged daughter, Hayley Smith; and their high-school-aged son, Steve Smith. Outside of the Smith family, there are three additional main characters, including Hayley's boyfriend turned husband, Jeff Fischer; the family's man-in-a-goldfish-body pet, Klaus; and most notably the family's zany alien, Roger, who is "full of masquerades, brazenness, and shocking antics."
Season 21
Francine joins Tuttle's gardening club, but he wants her gone. Meanwhile, the rest of the family practice the power of yes.
Francine and Roger become addicted to peeping in on people at a mysterious motel.
Season 22
Stan nearly dies on his 400th mission and returns home to realize the CIA's secret clone program has already replaced him.
In this three-part anthology of self-contained tales, the Smiths take on new roles across the harsh frontier of space, confronting mortality, purpose, and that relentless Mars dust.