In 1968 Detroit, aspiring record label executive Stix approaches three sisters – eldest Tammy aka "Sister", middle child Delores aka "Dee", and Sparkle, the youngest – to form a girl group after he sees Sister perform a song that Sparkle wrote at a nightclub. The girls are raised by their mother Emma, who disapproves of them singing outside of church. With Stix as their manager, they enter the talent show and wow the crowd with their performance, becoming a popular act in Detroit, but their fame is marred by personal struggles including Sister's toxic relationship with Satin and her spiraling into drug abuse.
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