Father and son coroners Tommy Tilden (Brian Cox) and Austin Tilden (Emile Hirsch), both experienced pathologists, are tasked with examining the mysterious and unidentified body of Jane Doe, whose recent death defies explanation. As they delve deeper into the autopsy, bizarre clues hint at a sinister supernatural force that was unleashed upon her, culminating in a terrifying ordeal of unexplained events, hallucinations, and gruesome discoveries.
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