A low-budget horror movie crew on location in Hawaii is attacked by a hybrid creature - half piranha and half anaconda - when one of its eggs is stolen. The crew must outrun and kill the deadly Piranhaconda as well as stop a mad scientist who stole the egg. Along the way, they're held hostage by criminals led by Michael Madsen's Professor Lovegrove teams up with his scriptwriter to escape their captors, but ultimately meet a gruesome demise at the hands of the monstrous creature and another deadly snake.
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