Dr. Herbert West continues his twisted research while serving a prison sentence for a past murder, sparking chaos when a new doctor and his brother, who was killed by West's experiments 13 years earlier, arrive on the scene. As West's experiments gain momentum, he revives his former victim with the help of the new doctor, but at a deadly cost. The prison descends into anarchy as the reanimated corpses spread chaos, forcing West to escape and continue his research in the shadows.
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