After Cacopoulos (Eli Wallach) manages to save himself from being hung on a false charge, he robs Cat Stevens (Terence Hill) and Hutch Bessy (Bud Spencer) of a lot of money and steals their horses. This results in a merry chase and Stevens and Bessy become unwilling allies in Cacopoulus' revenge against the people who deserted him and framed him to get their money back. They follow his trail south to Mexico, encountering people he has given money to, including a high wire performer Thomas (Brock Peters) and his assistant, before catching up with him in a village during a fiesta where Cacopoulos robs them again. He then sets out on a path of revenge against the remaining two men from his past who wronged him, using various tricks and disguises to track them down.