In 17th-century France, a young woman named Angélique de Sancé de Monteloup, from an impoverished noble family, is compelled into a marriage with the enigmatic Count Joffrey de Peyrac. Despite initial repulsion, Angélique comes to appreciate her unconventional husband's intelligence, kindness, and talent as a scientist and musician. As their marriage blossoms, she must navigate treacherous royal court politics when Joffrey's influence attracts suspicion and envy from powerful figures, leading to his false accusation of sorcery and treason. Devastated by grief, Angélique finds herself cast out, forced to survive in the perilous Parisian underworld, where her wit and beauty transform her into a resilient and resourceful woman determined to exact vengeance upon those who destroyed her life.