In 2026, a biochemist Dr. Hero Martins accompanies Pentagon bioterror operatives Robert Quinn and Trini Romano to an underground cold storage vault at the Atchison Storage Facility in Kansas, where an infectious fungus escaped from a sealed facility after a space station's oxygen tank landed in Western Australia. The three are joined by Travis "Teacake" Meacham, a night guard at the facility, who must survive the wildest night shift ever with Naomi Williams, his new colleague, to save humanity from extinction as the fungus starts to spread and turns people into violent, zombie-like creatures.
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