Dr. Peter Newmans (Johnny Simmons), a thirty-year-old sex therapist, undergoes a miraculous transformation after the removal of a benign tumor affecting his pituitary gland, causing him to experience puberty at age 27. As he navigates this sudden change, he becomes the object of affection for Michelle (Brittany Snow), leading to comedic misunderstandings and awkward encounters. With the help of his teenage neighbor, Peter eventually learns to control his newfound libido and finds love with Michelle, who becomes pregnant with their child.
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