Danny Garrison (Lee Montgomery) befriends Ben, a rat that becomes his best friend and leader of a pack of vicious killer rats, killing many people in their neighborhood. After some attacks on humans and a grocery store, police detective Cliff Kirtland (Joseph Campanella) tries to control the situation with traps and poison. Meanwhile, Danny's sister Eve is skeptical of Ben, but ultimately, a tearful Danny tends to the injured Ben after a violent confrontation between Ben's colony and the authorities ends in disaster.
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